Osteoarthritis affects approximately 32.5 million adults in the United States, creating a massive demand for alternatives to joint replacement surgery. According to the Centers for Disease Control and Prevention, nearly one in four adults with arthritis report limited activity due to joint pain. For patients in the Pacific Northwest, avoiding invasive procedures is often the primary goal. Oregon Regenerative Medicine has spent over 30 years pioneering non-surgical treatments for osteoarthritis in Portland and the surrounding regions. We utilize advanced regenerative therapies to restore function and eliminate pain without the risks of traditional surgery. (Contact Oregon Regenerative Medicine)
Diagnostic Precision and Imaging
Effective treatment begins with an accurate diagnosis. Many clinics rely solely on static X-rays, which often fail to capture the dynamic nature of soft tissue damage. At Oregon Regenerative Medicine, we utilize real-time ultrasound imaging to evaluate tendon, ligament, and joint disorders. This technology allows our physicians to see the exact source of pain during your examination. Ultrasound imaging is equal to or better than MRI in evaluating most tendon and ligament disorders in the arms and legs. This includes common conditions such as achilles tendinitis, tennis elbow, and rotator cuff tears. (Fluoroscopy Guided Spine Injections)
For spinal conditions, we employ fluoroscopic C-Arm guidance. This ensures that every injection is placed with millimeter precision. Getting the correct diagnosis quickly can mean weeks or months of your life back. Our approach eliminates the guesswork associated with blind injections. We separate out individual tendon, ligament, and fascia fibers to target the affected area directly. This level of precision is critical for treating osteoarthritis, which often involves complex interactions between bone, cartilage, and surrounding soft tissues. (PRP amp Biocellular Joint)
Platelet Rich Plasma (PRP) Therapy
Platelet Rich Plasma, or PRP, is a concentrated preparation of a patient's own blood. Platelet Rich Plasma is a regenerative medicine technique that uses autologous blood to accelerate healing in damaged tissues. The process involves drawing blood from the patient and spinning it in a centrifuge to isolate the platelets. Scientists have identified hundreds of growth and repair compounds in PRP. These growth factors stimulate the body's natural healing response. (How A2M Offers a)
Research supports the efficacy of PRP for knee osteoarthritis. A meta-analysis of randomized controlled trials published in the Journal of Orthopaedic Surgery and Research confirms that intra-articular PRP injections significantly reduce pain and improve function in patients with knee osteoarthritis. The study highlights that PRP provides superior outcomes compared to hyaluronic acid injections in many cases. By using your own biological material, we minimize the risk of allergic reactions or immune rejection. This makes PRP a safe and effective option for patients seeking to delay or avoid surgery. (Meet Our Team)
Stem Cell and Biocellular Therapies
For more advanced degeneration, we offer autologous Adipose Tissue Stem Cell Grafts. Adipose Tissue Stem Cell Grafts are biological treatments derived from the patient's own fat tissue to promote tissue regeneration. These cells, known as mesenchymal stem cells, have the unique ability to differentiate into various tissue types, including cartilage and bone. This therapy is particularly effective for severe osteoarthritis where cartilage loss is significant.
The regenerative capacity of adipose-derived stem cells is well-documented. Studies comparing mesenchymal stem cells from bone marrow and adipose tissue show that adipose-derived cells offer advantages in cell yield and ease of harvest. In clinical settings, these cells help regenerate cartilage in human knee osteoarthritis. Patients often experience durable pain-free function without the need for joint replacement. Our doctors are highly skilled in harvesting and processing these cells to ensure maximum potency. We use ultrasound guidance to ensure the cells are delivered exactly where they are needed most.
Prolotherapy for Joint Stability
Prolotherapy is a non-surgical treatment that involves injecting an irritant solution into damaged ligaments and tendons. Prolotherapy is a regenerative injection technique that stimulates the body to repair weakened connective tissues. The most common agent used is dextrose, a natural sugar that triggers an inflammatory healing response. This response brings blood flow and nutrients to the area, promoting the growth of new collagen fibers.
Prolotherapy is particularly effective for joints that have become lax due to osteoarthritis or previous injuries. A prospective open-label trial published in BMC Musculoskeletal Disorders demonstrated that dextrose prolotherapy significantly reduced pain and improved physical function in patients with knee osteoarthritis. The study noted that patients experienced sustained benefits over several years. By tightening lax ligaments, prolotherapy restores joint stability and reduces the abnormal wear and tear that accelerates arthritis progression.

Therapy Comparison and Selection
Choosing the right treatment depends on the severity of your osteoarthritis and your specific anatomical needs. The table below summarizes the key differences between our primary non-surgical therapies.
| Therapy | Primary Mechanism | Best For | Key Benefit |
|---|---|---|---|
| PRP Therapy | Growth Factor Release | Mild to Moderate Osteoarthritis | Anti-inflammatory and tissue repair |
| Stem Cell Therapy | Cellular Regeneration | Severe Cartilage Loss | Cartilage regeneration potential |
| Prolotherapy | Ligament Tightening | Joint Instability and Laxity | Improved joint stability |
Our team at Oregon Regenerative Medicine evaluates each patient individually. We consider your medical history, activity level, and imaging results to recommend the most effective protocol. Many patients benefit from a combination of these therapies for optimal results.
Key Takeaways
- Oregon Regenerative Medicine has performed over 40,000 regenerative injections for patients in the Pacific Northwest.
- Real-time ultrasound imaging allows for precise diagnosis and treatment of soft tissue injuries in Portland.
- PRP therapy utilizes your own blood to release growth factors that reduce inflammation and promote healing.
- Stem cell therapy using adipose tissue offers potential for cartilage regeneration in severe osteoarthritis cases.
- Prolotherapy strengthens lax ligaments, improving joint stability and reducing pain progression.
- Our doctors have decades of experience in both ultrasound and fluoroscopic guidance techniques.
- Most patients achieve durable pain-free function without the need for surgery or joint replacement.
Frequently Asked Questions
Is non-surgical treatment for osteoarthritis covered by insurance?
Insurance coverage for regenerative therapies like PRP and stem cell injections varies by provider and plan. Many patients pay out-of-pocket or use flexible spending accounts. We recommend contacting your insurance provider directly to verify your specific benefits.
How long does it take to recover from PRP injections?
Recovery time depends on the severity of the injury and the area treated. Most patients experience some soreness for a few days. Significant improvements in pain and function are typically noticed over several weeks as the healing process unfolds.
Are stem cell injections safe?
Yes, when performed by qualified professionals. We use autologous stem cells, meaning they are harvested from your own body. This eliminates the risk of immune rejection or disease transmission. Our procedures are conducted in a sterile, medical-grade environment.
Can prolotherapy cure osteoarthritis?
Prolotherapy does not cure osteoarthritis, but it can significantly slow its progression by stabilizing the joint. By tightening lax ligaments, it reduces abnormal wear on the cartilage. Many patients experience long-term pain relief and improved mobility.
What is the difference between PRP and stem cell therapy?
PRP relies on growth factors in your blood to stimulate healing. Stem cell therapy uses actual cells that can differentiate into new tissue. Stem cell therapy is generally reserved for more advanced cases where cartilage regeneration is needed.
Do you treat osteoarthritis in the spine?
Yes, we specialize in non-surgical treatment of spinal osteoarthritis. We use fluoroscopic guidance to ensure precise delivery of therapies to the affected spinal joints. This approach is highly effective for reducing back and neck pain.
How many sessions are typically required?
Some patients see improvement after a single session. Others may require a series of injections spaced several weeks apart. Our doctors will create a customized treatment plan based on your imaging results and clinical response.
Contact Oregon Regenerative Medicine
If you are suffering from osteoarthritis in Portland or the Pacific Northwest, do not settle for surgery or lifelong pain medication. Our team of expert physicians is ready to help you regain your active lifestyle. We are located inside the historic Foundry Building at Oswego Pointe. Contact us today to schedule your consultation and discover the power of regenerative medicine.

